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What is the difference between androgen insensitivity syndrome and gender dysphoria?

Dr. Jeanne Morrison, PhD
Family Practitioner

Androgen insensitivity syndrome is not the same thing as gender dysphoria. Androgen insensitivity syndrome is a genetic problem that affects sexual development. People with complete AIS have female physical characteristics, just no female reproductive organs. People with partial AIS may have ambiguous genitalia and physical characteristics of both males and females, and they may have either a female or male gender identity. AIS is often considered an intersex condition. In gender dysphoria, physical characteristics develop normally, but an individual feels that they have the "wrong" sex's physical characteristics. That means that genetic males with gender dysphoria feel like they're females, and genetic females may feel like they're actually males.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.