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What is Imlygic?

Imlygic (talimogene laherparepvec) is a modified herpes virus for the treatment of melanoma tumors that cannot be surgically removed from the skin or lymph nodes. It is injected directly into the tumors; the viruses kill the cancer cells and spur the body's immune system to also attack the cancer cells. Treatment lasts for about six months; the second treatment is given three weeks after the first, and then every two weeks. Imlygic is not recommended for pregnant patients or those with compromised immune systems. Safety has not been established for use in children. Side effects may include fatigue, nausea, chills, and fever. Herpes virus infection may occur as well. Imlygic has not been shown to help reduce melanoma that had spread beyond the skin or lymph nodes. Acyclovir and other antiviral medications should be avoided during treatment, as they can reduce the effectiveness of Imlygic. 

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