Advertisement

How do thyroid hormones affect fertility?

The importance of the thyroid hormone for the adequate functioning of multiple organ systems within the body cannot be overstated. The production of adequate quantities of thyroid hormones (thyroxine [T4] and triiodothyronine [T3]) is necessary for normal fetal and neonatal growth and development, as well as proper functioning of adult organ systems, including the skeletal system, the cardiovascular system, lipid and carbohydrate metabolism, and the neuromuscular system.

The major effects of abnormal thyroid levels relates largely to changes in ovulation and menstruation. Ovulation may be impaired by changes in the production of: sex hormone binding globulin (SHBG), follicle stimulating hormone (FSH), estrogen, and androgens to name a few. The body compensates by altering the production of thyroid releasing hormone (TRH) from the hypothalamus. The changes in TRH will affect the feedback loop between the hypothalamus, pituitary, and the ovary, leading to changes in ovulation and menstruation. These changes can be subtle, especially when symptoms of thyroid dysfunction are not obvious and do not lead to changes in menses or ovulation. Early stages of thyroid dysfunction (before symptoms are manifest) can lead to subtle changes in ovulation and endometrial receptivity, which then may have profound effects on fertility.

Continue Learning about Infertility

What intrauterine insemination ( iui) ?
Diana MeeksDiana Meeks
Intrauterine insemination (IUI) is an infertility treatment that is often called artificial insemina...
More Answers
when should donor eggs be used in fertility treatment ?
Greenville Health SystemGreenville Health System
Donor eggs should be used in cases when women produce eggs of poor quality for embryo development. T...
More Answers
7 factors that affect fertility
7 factors that affect fertility7 factors that affect fertility7 factors that affect fertility7 factors that affect fertility
one out of every eight couples have trouble getting pregnant or staying pregnant . infertility , or the inability to conceive , can be extremely emoti...
Start Slideshow
does infertility run in families ?
does infertility run in families ?

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.