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What causes hypogonadism?

Dr. Jeanne Morrison, PhD
Family Practitioner

There are two types of hypogonadism, and they each have different causes. Primary hypogonadism is caused by a problem in the actual sex gland. Causes of primary hypogonadism may include genetic disorders like Turner syndrome and Klinefelter syndome, undescended testicles, certain infections, radiation treatment or surgery, old age, and injury to the sex organs. Secondary hypogonadism (also called central hypogonadism) is caused by problems with the communication between the brain and the sex glands. Causes of secondary hypogonadism may include pituitary disorders, certain inflammatory diseases or infections, radiation and other medications, and brain tumors.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.