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What is lomitapide?

Donna Hill Howes, RN
Family Practitioner

Lomitapide (Juxtapid) is approved by the FDA for lowering total and LDL cholesterol in people with homozygous familial hypercholesterolemia (HoFH). HoFH is an inherited condition in which cholesterol levels are extremely high, often even with aggressive treatment with statins. Lomitapide works by binding to a protein required to build LDL cholesterol inside cells of the body. The effects of lomitapide on cardiovascular disease are not known.

Lomitapide is taken daily by mouth. 

This answer was adapted from Sharecare's award-winning AskMD app. Start a consultation now to find out what's causing your symptoms, learn how to manage a condition, or find a doctor. 

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.