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What is tumor lysis syndrome?

Tumor lysis syndrome is a condition caused by the destruction of a large number of tumor cells and the release of their contents into the bloodstream. It occurs most commonly when potent chemotherapy is used for hematologic cancers, especially acute leukemias and non-Hodgkin lymphoma. It causes high levels of potassium, uric acid, and phosphate, and low levels of calcium in the blood. The abnormal potassium and calcium levels can cause seizures and changes in heart rhythm, which may lead to cardiac arrest. Kidney impairment or even failure can occur because of uric acid crystals or calcium-phosphate stones collecting in the kidneys. Tumor lysis syndrome is a very serious condition that requires prompt and appropriate treatment by a doctor.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.