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How can gout attacks be prevented?

William J. Martin, MD
Rheumatology
Treatment for hyperuricemia (high uric acid level) to prevent gout attacks aims to block the formation of uric acid. This is done with the medications allopurinol or febuxostat. Doctors can also use the medication probenecid to increase the excretion of uric acid through the kidneys. Another medication, pegloticase, breaks down the uric acid directly (pegloticase can cause rash, bruising, nausea, antibody formation, severe allergic reactions, exacerbation of heart failure and hemolytic anemia).

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.