Does resveratrol interact with other medications?

Resveratrol does have some serious drug interactions, so you should not take it except under the care and explicit instruction of a physician. Taking resveratrol while also using anticoagulants ("blood thiner"), such as clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others, could cause increased bleeding. Resveratrol seems to have antiplatelet effects, so, taking resveratrol with other antiplatelet drugs might increase the risk of bruising and bleeding. Some of these drugs include nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin, diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others).

If you are pregnant or breast feeding resveratrol may not be right for you. Tell your doctor about all medications, vitamins, herbal supplements, or dietary choices you are currently making so that they can decide if resveratrol is safe for you. In particular, mention herbs like angelica, clove, danshen, feverfew, garlic, ginger, ginkgo, ginseng Panax, horse chestnut, red clover, turmeric, and others.

Preliminary evidence shows that resveratrol might increase levels of drugs metabolized by certain enzymes. However, this interaction has not been reported in humans. Some drugs metabolized by these enzymes include lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), and numerous others. Use resveratrol cautiously or avoid in patients taking these drugs.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.