Genitourinary Agent

Genitourinary Agent

Genitourinary Agent
Genitourinary drugs treat genitourinary disorders affecting the kidneys, ureters, bladder and uretha.

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    Tolterodine has the brand name Detrol or Detrol LA.   It is marketed to have fewer side effects, like dry mouth or constipation, than oxybutynin.  Dry mouth is the most common side effect with tolterodine.  Oxybutynin has a much higher reported rate of side effects, especially those like dry mouth and constipation.
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    Peritoneal dialysis solution is a cleansing liquid that is infused through a catheter (a soft tube) into the abdominal cavity. This solution is used during peritoneal dialysis to pull wastes and liquid from the blood. Peritoneal dialysis is an alternative to the kind of dialysis most people are familiar with -- hemodialysis, in which blood from a patient is run through a dialysis machine that removes wastes and liquid. Either kind of dialysis keeps the blood clean when the kidneys fail.

    Peritoneal dialysis solution is a mixture of dextrose (or another sugar), salt and minerals dissolved in water. The solution fills the abdomen, and waste materials mix with the solution. They are removed from the body when the solution is drained away. This process is called an exchange.
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    Pentosan polysulfate is used to treat interstitial cystitis, a bladder disease that causes swelling and scarring of the bladder wall. It helps relieve symptoms of interstitial cystitis by preventing irritation of the bladder wall. Pentosan polysulfate is related to a class of medicines called low molecular weight heparins. It comes as capsules that you swallow. Brand names for pentosan polysulfate include Elmiron.
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    Based on information from iGuard.org, a free medication monitoring service, 23% of patients experience side effects while taking Pentosan Polysulfate Sodium (Elmiron). Some of the side effects reported by iGuard members include: Headache, Abdominal Pain/Cramps, Urinary Retention, Bone/Joint Pain, Vision Changes, Dizziness, Bleeding, Fatigue, Weight Gain, Hair Loss, and Dryness. Please follow up with your doctor or other healthcare provider if you are experiencing any symptoms that worsen or do not go away.

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    There is a risk of side effects while taking pentosan polysulfate. Call your doctor right away if you experience abnormal bleeding or bruising, blood in your urine, or feeling faint. Some less serious side effects may include stomach pain, diarrhea, nausea, dizziness, mild skin rash or itchiness, hair loss, difficulty sleeping, moodiness, or heartburn. If these symptoms become severe or won't go away, talk to your doctor.
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    Before taking lanthanum, share your complete medical history and health status with your doctor. Tell your doctor if you currently have Crohn's disease, ulcerative colitis, a stomach ulcer, intestinal or stomach problems or a bowel obstruction and if you've ever experienced an allergic reaction to lanthanum, any other medication, food, dye or preservative. Make sure your doctor knows all the medications you're taking, including over-the-counter or herbal medications.
    Among the drugs that can interact with lanthanum are acid blockers, beta blockers, aspirin and similar drugs, captopril, chlorpromazine, digoxin, isoniazid, iron products, ketoconazole, levodopa, anxiety or sleep medications, blood clot medications (e.g., warfarin), seizure medications, nitrofurantoin, NSAIDS e.g. ibuprofen and naproxen), quinidine, quinolone antibiotics, steroid medicines (e.g., prednisone or cortisone), sodium polystyrene sulfonate or tetracycline antibiotics. You may have to take lanthanum separately from other medications, because lanthanum may affect how the other medications are absorbed into your system.
    While studies have not definitively shown that lanthanum is harmful to unborn babies, if you are pregnant or planning to become pregnant or if you are breastfeeding, let your doctor know. While taking lanthanum, be sure to follow your prescribing doctor's instructions. Take the medicine during or immediately following meals, and always chew the tablets completely before swallowing. If you require an x-ray while using this medication, inform the technician that you are taking lanthanum.
     
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    Pentosan polysulfate comes as capsules that you swallow. You should take this medicine with water at least one hour before or two hours after each meal. Take this medicine exactly as your doctor tells you.
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    Also known as the brand product Fosrenol, lanthanum is a prescription medication for people with kidney disease. A phosphate binder, the medication is prescribed in chewable tablet form to help lower phosphate levels in the blood, which can rise if the kidneys are not working properly. Lanthanum prevents the absorption of phosphate from foods in the stomach.

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    Common, less serious side effects of taking lanthanum include: diarrhea, constipation, nausea, vomiting, stomach pain, headaches and runny nose.

    If you experience any signs of an allergic reaction, such as difficulty breathing, hives or swelling in the face, tongue, lips or throat, call 911 immediately. Other potentially serious side effects include: confusion, irritability, tiredness, weakness, faintness, fever, infection, appetite loss, low blood pressure, blurred vision, dizziness or a blockage at a dialysis graft. Let your doctor know if you experience any of these side effects.

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    Before you take pentosan polysulfate, tell your doctor if you have allergies to this drug, danaparoid, heparin, or any other medicines. You should also tell your doctor if you have any problems with bleeding or blood clotting, history of stroke or aneurysm, stomach disorders, spleen or liver disease, hemophilia, ulcers, or intestinal blockage. If you are pregnant, thinking of becoming pregnant, or breastfeeding, talk to your doctor before taking pentosan polysulfate. Some over-the-counter or prescription medications may increase your risk of bleeding. These include anticoagulants such as warfarin, aspirin, alteplase, anistreplase, clopidogrel, dipyridamole, streptokinase, ticlopidine, urokinase, or nonsteroidal anti-inflammatory drugs (NSAIDs). If you are taking any of these medicines, talk to your doctor before taking pentosan polysulfate.