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What are urinary anticholinergics?

Donna Hill Howes, RN
Family Practitioner

Urinary anticholinergics are drugs that relax the bladder, increasing its capacity and reducing pressure. They are sometimes used to treat urinary symptoms of an enlarged prostate, such as needing to urinate urgently and often. They are not FDA-approved for this use.

Urinary anticholinergics used for bladder symptoms include darifenacin (Enablex), fesoterodine (Toviaz), oxybutynin (Ditropan, Gelnique, Oxytrol), solifenacin (Vesicare), tolterodine (Detrol), and trospium (Sanctura). Extended-release formulations, which are often better tolerated, are available for most of these. 

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