Gastrointestinal Agent

Gastrointestinal Agent

Gastrointestinal Agent
Gastrointestinal drugs treat nausea, diarrhea, and ulcers. Some of these drugs are classified as antcholinergics, antidarrrheals, and antiulcer medications.

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    Cholbam is a bile acid synthesis intended for the treatment of genetic illnesses that prevent the creation of the body's own cholic acid. Normally the liver creates cholic acid from cholesterol, but patients with disorders like Zellweger syndrome, or single peroxisomal enzyme / transporter deficiencies (PEDs), are unable to do this. Primary bile acids like cholic acid aid fat digestion and absorption, necessary for building nerves and brain tissue, and for proper organ function. Without primary bile acids, infants with these inherited diseases cannot develop properly. Older patients whose disease manifests itself later in life may develop partial paralysis, Addison's disease, and other signs. Cholbam may be used in patients as young as three weeks. It is administered as a capsule taken once or twice daily with food.
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    Belbuca (buprenorphine) is a powerful opioid painkiller for the management of severe, constant pain that cannot be managed by nonopioid painkillers. Belbuca comes in a film that is applied on the inside of the cheek, twice a day. The film dissolves within half an hour. Patients must avoid eating or drinking until the film has dissolved. Side effects may include gastrointestinal problems (constipation, nausea, etc.), seizures in patients with seizure disorders, poor motor control, and sleepiness. Opioid painkillers have a serious risk of addiction, overdose, and may cause life-threatening breathing problems, especially if combined with other depressants like alcohol. Pregnant women, nursing mothers, and patients with severe asthma, a history of substance abuse problems, gastrointestinal blockage, or sensitivity or allergy to buprenorphine may be cautioned against taking Belbuca. 
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    Lipase is an enzyme that is produced primarily in the pancreas, but also in the mouth and stomach. It is released by the pancreas into the small intestine, where it helps to break down the fat you eat so that it can be absorbed by the body.

    It is normal to have a small amount of lipase in your blood. However, abnormally high levels of lipase in the blood may be a sign that the pancreas is damaged or diseased, or that the pancreatic duct is blocked. Your doctor may order a blood test to check the level of lipase in your blood if you are experiencing symptoms of a potential problem with your pancreas. A lipase blood test can also be one tool in diagnosing a bowel obstruction, duodenal ulcers or celiac disease. It is also used to diagnose familial lipoprotein lipase deficiency, rare inherited conditions that cause a lack of lipase.
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    The pancreas releases the digestive juices (enzymes) needed to take nutrients out of our food and put them into our body. To do this, the pancreas has a complicated system of ducts that collect and transport digestive enzymes. Through these ducts, the enzymes are led to the duodenum, the upper part of the small intestine. The nutrients of the food are then absorbed in the small intestine.
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    Here are some stool softener precautions:
    • Don't use stool softeners if you have severe stomach pain, nausea, diarrhea, or vomiting.
    • To avoid dependency, don't use stool softeners for longer than one week, unless approved by your healthcare provider. (If you're taking pain pills, you may need to continue taking stool softeners until you're finished taking the pain pills.)
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    Stool softeners make bowel movements easier. They are commonly prescribed after heart surgery to prevent straining and to get your digestive system functioning normally again. Examples of stool softeners include:
    • docusate calcium (Surfac)
    • docusate sodium (Colace)
    • docusate sodium and casanthranol (Pericolace)
    • DOS
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    The proton pump inhibitor (PPI) you've been using for acid reflux may contribute to bone loss. There's evidence that PPIs weaken bones, partly by interfering with calcium absorption. Usually, this only increases fracture risk at high doses or over a long period of time.

    Talk with your doc about swapping your PPI for an H2 antagonist ( “H” is for histamine) such as Zantac, Pepcid or Tagamet. There's evidence that H2 antagonists are not associated with fractures and may even protect bones.
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    A , Pharmacy, answered
    Talk with your doctor or pharmacist before taking the antibiotic methenamine with an Alka-Seltzer product. The brand name Alka-Seltzer refers to a variety of products that treat an array of conditions, and some of them may interact with methenamine. If your doctor says it's okay for you to combine methenamine with the indigestion medicine Alka-Seltzer Heartburn (sodium bicarbonate), be sure to take them at least two hours apart to minimize your chance of complications.
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    A , Pharmacy, answered
    If you are taking methotrexate, you should talk to your doctor or pharmacist before taking an Alka-Seltzer product. The name Alka-Seltzer refers to a family of products with various ingredients, and some of those products may cause problems if taken with methotrexate. Alka-Seltzer Heartburn (sodium bicarbonate), for example, is known to interact with methotrexate. If your doctor says it's okay to take both, be sure to take them at least two hours apart to avoid complications.
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    If you are taking a sulfa-containing antibiotic, be sure to check with your doctor if you plan to also take an Alka-Seltzer product. The name Alka-Seltzer refers to a family of products with various ingredients, some of which, such as those in Alka-Seltzer Heartburn (sodium bicarbonate), have been known to interact with these antibiotics. If your doctor or pharmacist tells you it is okay, be sure to take these medicines at least two hours apart from each other to avoid complications.