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How is the stratum corneum different from the epidermis as a whole?

Dr. Mehmet Oz, MD
Cardiology (Cardiovascular Disease)

The stratum corneum is the epidermis' protective outer layer. The stratum corneum is composed of cells, cushioned by layers of lipids. So, if the epidermis as a whole is the body's first line of defense against the environment, the stratum corneum acts as the barrier or seal, to keep the contents of the skin intact and optimally hydrated.

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