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Are there any risks in taking fluoxetine (Prozac)?

The most serious risk in taking fluoxetine (brand name Prozac) is the potential for worsening depression and suicidal thoughts. An additional and common risk is drowsiness; check with your doctor about driving, drinking alcohol, and taking other medications while taking fluoxetine. In people with diabetes, blood sugar may be affected. A rare condition known as serotonin syndrome which can lead to rapid or irregular heart rate, changes in blood pressure, confusion, diarrhea, nausea, vomiting, hallucinations, seizures, and even coma, is also possible. Fluoxetine can pose a risk for a person who is suffering from bipolar disorder, so be careful to determine that your depression is not a symptom of an underlying bipolar disorder. Fluoxetine may also cause intestinal bleeding which is exacerbated by nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin or ibuprofen. People who have a heart rhythm disorder called long QT syndrome, or who have a family history of or risk factors for the syndrome, should be monitored closely while taking fluoxetine. Finally, people who are elderly should use fluoxetine with care, as it may cause their blood sodium to become low.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.