What are estrogen secreting tumors?

Estrogen secreting tumors cause a feminizing syndrome. They may or may not cause signs and symptoms depending on the age and sex of the patient. In boys who have not reached puberty, they can cause breast enlargement (gynecomastia) and delayed or absent pubic hair, as well as delayed penis growth. For older males, they can lead to gynecomastia, decreased sperm production, decreased pubic hair, and testicle and penis atrophy (shrinking). In girls who have not reached puberty, these tumors can lead to early puberty and early start of periods (menarche). Premenopausal women may have disturbances in menses. Postmenopausal women may develop vaginal bleeding.

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