What are the symptoms of multiple endocrine neoplasia type 2 (MEN2)?

Multiple endocrine neoplasia type 2 (MEN2) causes different symptoms depending on which glands are affected.

MEN2 tumors in the parathyroid glands mess up the body's calcium balance. Too many hormones released by the tumor means too much calcium in the blood. This makes people feel tired and weak. The extra calcium also makes people thirsty, so they feel like they need to pee all the time. Too much calcium also causes muscle weakness and bone pain, and over time, can damage the kidneys.

A MEN2 tumor in the adrenal glands causes the glands to produce more adrenaline than the body needs. Too much adrenaline from tumors in the adrenal glands can make people feel sweaty and anxious. People can get headaches too, and it might feel like their heart is beating really fast.

Tumors in the gut can make people constipated, or even sometimes cause diarrhea.

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