What should I know about propylthiouracil before taking it?

Propylthiouracil (PTU) can cause life-threatening liver damage, so it is important to let your doctor know if you have a history of liver problems. Signs of liver damage include: abdominal pain over the upper right side, loss of appetite, yellow discoloration of the skin or eyes (jaundice), fatigue, brown urine and excessive itching. Propylthiouracil can also cause a decrease in white blood cells, which can make you susceptible to infections, and a low platelet count, which can lead to bleeding or spontaneous bruising. If you have a history of decreased white blood counts (leukopenia), low platelets or aplastic anemia (inability to form new blood cells), let your doctor know.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.