What are the side effects of mannitol?

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Some of the side effects commonly associated with mannitol include: a mild rash, chills, electrolyte imbalances, dry mouth, increased thirst, a runny nose, nausea or feeling dizzy. Severe allergic responses to mannitol can include: hives, breathing problems and swelling in and around your face, mouth or tongue. Serious side effects include: rapid weight gain, swelling or noticeable skin changes at the injection site, the inability to urinate, a sudden spike in blood pressure, chest pain, shortness of breath, blurred vision and seizures. If you experience any allergic reactions or serious side effects seek immediate medical attention.