What is Aldactone (spironolactone)?

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Aldactone (spironolactone) is a prescription drug that treats high blood pressure, usually in combination with other drugs. Aldactone also is used to treat fluid retention (edema) caused by congestive heart failure, liver disease or kidney disease. Aldactone also treats hyperaldosteronism, a condition in which the adrenal glands produce too much of the hormone aldosterone, which can lower potassium levels in the blood and lead to health problems.

Aldactone is an aldosterone receptor antagonist. It works by blocking the hormone aldosterone. This makes the kidneys pass water and sodium from the body into the urine without losing too much potassium, allowing the body to safely eliminate excess fluid from edema and lowering blood volume, which helps lower blood pressure.