Who should not take spironolactone (Aldactone)?

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Certain people should not take spironolactone (Aldactone) because of an increased risk of harmful side effects. If you are allergic to any ingredients in spironolactone, do not take this medication. People with urination problems, kidney disease, and high blood potassium levels should not take spironolactone. You also shouldn't take spironolactone if you're taking certain other medications, including potassium supplements and other diuretics. Talk to your doctor before taking spironolactone if you have liver disease. If you drink alcohol or have a diet that's high in salt, you should talk to your doctor about lifestyle modifications before taking spironolactone.