What should I avoid while taking spironolactone (Aldactone)?

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While taking spironolactone, there are certain things you should avoid in order to prevent complications or serious side effects. Don't use other diuretics or potassium supplements while taking this medication, because this might cause blood potassium levels to become dangerously elevated. You should also avoid using salt substitutes that contain potassium, since these products may also affect blood potassium levels. Avoid drinking alcohol while taking spironolactone, because this may increase the risk for serious side effects. Avoid a high-sodium diet which will render spironolactone less effective. Also, avoid becoming either dehydrated or over-hydrated while taking this medication.