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Does hydrochlorothiazide interact with other medications or food?

If you take the following medications while taking hydrochlorothiazide (HCTZ) capsules, you will have an increased risk of developing an irregular heartbeat: digoxin, dofetilide and ketanserin. Tell your doctor if you are taking barbiturates, corticotropin, corticosteroids, narcotics, cholestyramine, colestipol, nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, diazoxide or lithium. People taking insulin or oral medications for diabetes should know that the medicine's effectiveness may be decreased while taking hydrochlorothiazide.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.