How does spironolactone treat hypokalemia?

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As a potassium-sparing diuretic, spironolactone helps the kidneys better process liquid waste without lowering potassium levels, which then reduces the amount of water your body retains. Hypokalemia is defined as low levels of potassium in the body. Potassium levels are usually affected by diet, some diuretics, diarrhea, laxatives or kidney failure. Hypokalemia may cause weakness, muscle cramps, constipation or an abnormal heart rate. Spironolactone has been known to help prevent hypokalemia by increasing the efficiency of the kidneys and blocking the function of a hormone called aldosterone, both of which can help balance sodium and potassium levels with the amount of fluid in your body. Spironolactone is typically used when other medications or procedures that increase the body's potassium levels are unavailable. Ask your doctor if spironolactone is the right treatment for your hypokalemia.