Do thiazide diuretics interact with other medications?

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Dr. Darria Long Gillespie, MD
Emergency Medicine
If you are taking digoxin or a loop diuretic, a thiazide diuretic may not be a good option for you.

If you are taking dofetilide, you should not take a thiazide diuretic.

If you are taking an ACE inhibitor, a thiazide diuretic may not be a good option for you.

If you are taking carbamazepine, cyclophosphamide, diazoxide, digoxin, an opioid, or oxcarbazepine, a thiazide diuretic may not be a good option for you. 

If you are taking a QTc interval prolonging drug, calcium channel blockers can lead to serious side effects.

This answer was adapted from Sharecare's award-winning AskMD app. Start a consultation now to find out what's causing your symptoms, learn how to manage a condition, or find a doctor.
 

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