Who should not use topical urea to treat skin problems?

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Topical urea is safe for use by most people. However, you should not use topical urea medications to treat skin problems if you're allergic to any product ingredients. Also, do not use topical urea if your skin is broken or extremely irritated. In addition, talk with your doctor before using topical urea if you're pregnant or breastfeeding, as the product can affect a fetus or breastfeeding child.