What are the side effects of hydroquinone 3% topical solution?

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While using hydroquinone 3% topical solution, you may experience burning, stinging, itching, irritation in the treated areas and develop acne. If these side effects do not go away or get worse, contact your doctor. Also let your doctor know right away if you experience any of the following side effects:

  • signs of an allergic reaction, such as hives or an itchy rash, swelling around the mouth or face
  • chest tightness and difficulty breathing
  • if the stinging, burning or irritation becomes severe
  • if you notice increased hair growth or inflamed hair follicles
  • if your skin becomes thinner, softer, loses color or becomes discolored
  • if you gain weight unexpectedly, particularly around the face

Seek medical assistance as these may be signs of an emergency. You should also contact your doctor right away if you notice that your skin has taken on blue-black coloration. People of African descent who are using this medication are more likely to experience this particular side effect.