What is ectopic ACTH syndrome?

A very rare condition, called ectopic (outside location) ACTH (adrenocorticotropic hormone) syndrome, accounts for less than 1% of cases of Cushing's syndrome. It means that a tumor lying outside of the pituitary gland is making too much ACTH. The most common places for an ectopic ACTH-producing tumor are in the lung and thymus, both located in the chest. Other very rare places include the thyroid, ovary, adrenal gland, and liver. Just like a pituitary adenoma, these ACTH-producing tumors make too much ACTH and in turn cause the adrenal glands to make too much cortisol.  

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