What side effects does methylprednisolone (Medrol) cause?

Based on information from, a free medication monitoring service, 78% of patients experience side effects while taking Methylprednisolone (Medrol). Some of the side effects reported by iGuard members include: Weight Gain, Hair Growth, Palpitations, Skin/Nail Problems, Insomnia, Nausea/Vomiting, Hair Loss, Drowsiness, Bone Loss, Mood/Behavior Changes, and Swelling/Edema. Please follow up with your doctor or other healthcare provider if you are experiencing any symptoms that worsen or do not go away.

Methylprednisolone can cause a variety of side effects. Stop taking methylprednisolone and seek emergency medical treatment if you have symptoms of an allergic reaction such as hives, trouble breathing or swelling of the tongue, face or throat. Call your doctor right away if you experience other serious side effects, such as vision changes, high blood pressure accompanied by anxiety, chest pain, confusion, irregular or elevated heartbeat, seizure, swelling or rapid weight gain, thirst, increased urination, weakness, leg discomfort, severe depression or mood changes, strong pain in your upper stomach and/or back with nausea and vomiting, black, sticky stools and coughing up blood.

Call your doctor only if the following side effects are bothersome or persistent: insomnia, headaches, dizziness, nausea, stomach pain, bloating, increased output of sweat, mood changes, acne, dry or thinning skin, increased hair growth, irregular menstruation, bruising, slow healing of wounds or changes in the location or shape of fat on your body.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.