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How common is sickle-hemoglobin C (Hb S-C) disease?

When similar hemoglobin disorders are concerned, sickle-hemoglobin C disease is actually more common than some. For instance, the disorder is more common than sickle cell anemia. Sickle cell anemia requires both parents to carry the mutated gene in order for a child to display symptoms. But sickle-hemoglobin C allows each parent to have a different kind of mutated gene-one for sickle cell anemia and the other for hemoglobin C disease. For this reason, it is more likely that a child will display symptoms of sickle-hemoglobin C (Hb S-C) disease than sickle cell anemia.

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