Advertisement

What is lipoid proteinosis (LP)?

Lipoid proteinosis (LP) is a rare disease that affects the skin and the brain. Three distinctive features characterize the disease: a hoarse voice, unusual growths on the skin and mucus membranes, and damage to the temporal lobes or hippocampus of the brain. The symptoms of LP may begin as early as infancy with hoarseness or a weak cry, due to growths on the vocal cords. Skin lesions appear sometime in the next 3 years, leaving acne- or pox-like scars on the face, hands and mucous membranes. The most characteristic symptom of LP is waxy, yellow, bead-like bumps along the upper and lower edges of the eyelids. Brain damage develops over time and is associated with the development of mental retardation and epileptic seizures. Damage to the amygdala, a part of the brain that regulates emotions and perceptions, leads to difficulties in discriminating facial expressions and in making realistic judgments about the trustworthiness of other people. LP is a hereditary disease that equally affects males and females.

This answer is based on source information from the National Institute of Neurological Disorders and Stroke.

Continue Learning about Autosomal Recessive Genetic Disorders

Are there alternative treatments for autosomal recessive genetic disorders?
Honor Society of Nursing (STTI)Honor Society of Nursing (STTI)
There are alternative and experimental treatments available for some autosomal recessive genetic dis...
More Answers
Do autosomal recessive genetic disorders run in families?
Honor Society of Nursing (STTI)Honor Society of Nursing (STTI)
Yes, autosomal recessive genetic disorders run in families. The only way to have an autosomal recess...
More Answers
Why do people with congenital adrenal hyperplasia (CAH) get sicker than others?
Jumo HealthJumo Health
People with congenital adrenal hyperplasia (CAH) get sicker than others because their blood sugar le...
More Answers
What is an autosomal recessive condition?
Brigham and Women's HospitalBrigham and Women's Hospital
In an autosomal recessive condition there is a mutation in both copies of a gene (the basic unit...
More Answers

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.