What is congenital adrenal hyperplasia (CAH)?

Congenital adrenal hyperplasia (CAH) is a condition a person is born with (congenital) in which their adrenal glands are larger than normal (hyperplasia). Their adrenal glands can't make the hormone cortisol or enough of the hormone aldosterone. They go into overdrive trying to make enough hormones, and as a result, get bigger and bigger than usual. There are four types of CAH: classic, salt-losing, non-salt-losing and late-onset CAH.

A rare cause of male factor infertility, congenital adrenal hyperplasia (CAH) involves congenital deficiencies in certain enzymes, resulting in abnormal hormone production. CAH is usually diagnosed by demonstrating excess steroids in the blood and urine. When treated successfully with hormone replacement, sperm production increases.

Continue Learning about Autosomal Recessive Genetic Disorders

How do I manage my Gaucher disease on a daily basis?
Jumo HealthJumo Health
To help manage your Gaucher disease on a daily basis, keeping fit and eating lots of healthy food ar...
More Answers
How is congenital adrenal hyperplasia (CAH) treated?
Jumo HealthJumo Health
Doctors can treat congenital adrenal hyperplasia (CAH) by giving people hormones to replace the ones...
More Answers
How is neuronal ceroid lipofuscinoses (NCL) inherited?
Honor Society of Nursing (STTI)Honor Society of Nursing (STTI)
Childhood NCL is an autosomal recessive disorder; that is, it occurs only when a child inherits two ...
More Answers
What is the chance of having a child with an autosomal recessive condition?
Brigham and Women's HospitalBrigham and Women's Hospital
In an autosomal recessive condition there is a mutation in both copies of a gene (the basic unit...
More Answers

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.