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What is mitoxantrone?

Donna Hill Howes, RN
Family Practitioner

Mitoxantrone is a drug that works by suppressing the immune system. It is also used to treat leukemia and breast cancer. It is approved for treating secondary-progressive, progressive-relapsing, and relapsing-remitting multiple sclerosis (MS) that is getting worse. It is given as an intravenous (IV) infusion, usually every 3 months. It is not a first-line drug treatment for relapsing-remitting MS. It can cause serious side effects that limit its use for people with less severe or more stable MS.

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