What are the side effects of repaglinide and metformin?

Common side effects of repaglinide and metformin (PrandiMet) include diarrhea, nausea and vomiting at the beginning of treatment. Other side effects include hypoglycemia (low blood sugar), upper respiratory infections (colds) and headaches.

More rarely, repaglinide and metformin, which is used to treat type 2 diabetes, may cause a serious side effect called lactic acidosis. People with kidney problems are especially at risk. Symptoms include tiredness, not feeling well in general, trouble breathing, muscle pain and abdominal pain. Call for emergency help right away if you develop these symptoms while taking repaglinide and metformin.

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