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How does protriptyline work?

Experts are not sure exactly how or why protriptyline works. Based on some studies, it seems that protriptyline works by increasing the amount of the brain chemicals (neurotransmitters) called norepinephrine and serotonin. It does this by blocking the ability of these chemicals from going back into the nerve cells. Experts believe that low levels of these substances may contribute to feelings of depression, so having more serotonin or norepinephrine in your system may help improve symptoms of depression.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.