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How does fluoxetine hydrochloride interact with other drugs?

Fluoxetine hydrochloride can interact with many other drugs. It should never be mixed with MAO inhibitors or thioridazine. Do not take fluoxetine hydrochloride if you are taking these drugs or if you have taken them within the past two weeks.

Talk to your doctor about taking fluoxetine hydrochloride if you are taking any of the following:

  • Carbamazepine
  • Digitoxin
  • Diazepam
  • Alprazolam
  • Aspirin
  • Clozapine
  • Other antidepressants
  • Sleeping aids, tranquilizers, or sedatives
  • Narcotics
  • Haloperidol
  • Lithium
  • Flecainide
  • Non-steroidal anti-inflammatory drugs
  • Anticoagulants
  • Phenytoin
  • Sumatriptan
  • Vinblastine
  • Ketoprofen
  • Pimozide
  • Protriptyline
  • Trimipramine
  • Clopidogrel
  • Diuretics
  • Almotriptan
  • Amoxapine
  • Clomipramine
  • Desipramine
  • Doxepin
  • Imipramine
  • Nortriptyline
  • Tryptophan
  • St. John's Wort
  • Eletriptan
  • Tramadol
Talk to your doctor about any other prescription or over-the-counter drugs, vitamins, and supplements you are taking before you take fluoxetine hydrochloride.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.