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What should I know about selegiline before taking it?

Selegiline may be needed to complement your current Parkinson's treatment, but there are numerous side effects to consider. Additionally, there are numerous precautions related to other medications and possible interactions. Significant adverse effects can result from using selegiline and antidepressants at the same time. In senior adults, there is an increased risk of orthostatic hypotension, an abrupt drop in blood pressure when changing from reclining or sitting to a standing position. Those with Parkinson's disease are at an increased risk of developing melanoma, or skin cancer. Selegiline can cause a reprise of the side effects of levodopa.

Women should not take selegiline if pregnant or breastfeeding; the effects on a fetus have not been studied. Selegiline has not been tested in children younger than 16 years of age. Some people may need to modify their diet due to possible interactions with certain foods, such as aged cheeses and meats, pickled herring, beer and wine that may cause an increase in blood pressure.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.