How does Divalproex Sodium ER interact with other medications?

Divalproex Sodium ER can interact with other medications and cause mild to severe side effects. These medications include aspirin, depression, anxiety, or psychotic medications, barbiturates, blood clot preventatives, isoniazid, seizure medications, meropenem, diazepam, tolbutamide, rifampin, and zidovudine. Before you begin this or any other medical treatment, you should make a list for your doctor of all medications you are currently taking including prescription, herbal, and over-the-counter medications.