How soon will I see my acne improve after I start using adapalene lotion?

You may begin to see results in eight to 12 weeks after starting. Pimples may take six to eight weeks to pop up from the time they start forming under your skin. During the first weeks of your treatment, adapalene lotion may brings pimples to the surface and make your skin look worse. Don't be worried if it does. Your acne most likely will improve with continued use.