How soon will isoniazid, pyrazinamide and rifampin help my symptoms?

If you have tuberculosis (TB), it is possible that you could start feeling better a few weeks after you start taking isoniazid-pyrazinamide-rifampin (Rifater). However, you must not stop taking this drug early. You will probably need to take this combination antibiotic for at least two months before switching to other drugs to fight the disease.