Suramin is an anti-neoplastic agent that has been used in the treatment of several infectious diseases, including African sleeping sickness (trypanosomiasis), a protozoan infection. African sleeping sickness is caused by an infection of the protozoa Trypanosoma, which can be contracted from a bite from a tsetse fly. Suramin treatment focuses on a particular stage of trypanosomiasis and is not effective if the protozoa has infected the central nervous system. Suramin also has been used to treat river blindness, although it is now used less frequently for this purpose because of recent studies on its toxicity. River blindness, or onchocerciasis, is caused by a roundworm and can eventually lead to blindness. Research also is being conducted on suramin's usefulness in treating people with different types of cancer. Suramin is only available from the Centers for Disease Control and Prevention as an investigational drug.
Anti-Infective Agent
Anti-infective is a drug or substance that kill an infection or prevent the infection from spreading.
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Stacy Wiegman, PharmD , Pharmacy, answeredIsoniazid-pyrazinamide-rifampin, a combination antimicrobial drug used to treat tuberculosis (TB) infection, carries risks of side effects ranging from vision problems to hepatitis. The combination carries the same risks as each of the components: isoniazid, pyrazinamide and rifampin. Your doctor should monitor you for these problems while you are taking this drug.
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Stacy Wiegman, PharmD , Pharmacy, answeredTake a missed dose of isoniazid-rifampin right away, unless you are almost due for your next dose. In that case, you should skip the dose you missed and return to your normal dosing schedule. Never take a double dose of this drug. Be sure to let your doctor know that you missed a dose.
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1 AnswerA
Stacy Wiegman, PharmD , Pharmacy, answeredTake a missed dose of isoniazid-pyrazinamide-rifampin (Rifater) right away, unless you are almost due for your next dose. In that case, you should skip the dose you missed and return to the normal dosing schedule. Never take a double dose of this drug. Be sure to let your doctor know that you missed a dose.
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Stacy Wiegman, PharmD , Pharmacy, answeredIsoniazid is an antitubercular drug sold under the generic name only. It is used orally or intravenously to treat Mycobacterium tuberculosis (TB) infections.
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Stacy Wiegman, PharmD , Pharmacy, answeredDo not take isoniazid-pyrazinamide-rifampin (Rifater), a combination drug used to treat tuberculosis (TB), if you have the following: severe liver disease; gout or other painful joint conditions; serious side effects from past use of isoniazid, including arthritis, fever or chills; medication-induced hepatitis; an allergy or sensitivity to any of the drug's ingredients. You also should not take isoniazid-pyrazinamide-rifampin with the following medications: lapatinib or other tyrosine kinase receptor inhibitors; ranolazine; temsirolimus; and voriconazole. If you need one of these medications, you and your doctor must decide which disease needs to be treated first (probably the TB) and which to postpone.
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Stacy Wiegman, PharmD , Pharmacy, answeredFirst, you must avoid missing any doses of the TB drug isoniazid. Your doctor should give you a list of foods to avoid if you are taking it. The foods to avoid include: aged cheeses, avocados, bananas, raisins, sour cream, soy sauce, some sausages and meats, including liver; some fish, including skipjack, tropical fish and tuna, beer and red wine. You should restrict alcohol consumption while taking isoniazid because it boosts your risk for liver problems.
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1 AnswerA
Stacy Wiegman, PharmD , Pharmacy, answeredTake a missed dose of isoniazid as soon as you remember it, unless you are almost due for your next dose. In that case, you should skip the dose you missed and return to your normal dosing schedule. Never take two doses of isoniazid at the same time.