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What should I know about Limbitrol DS (chlordiazepoxide amitriptyline DS)?

People taking antidepressants, and particularly people 24 years of age or younger, can experience suicidal thoughts. See your doctor regularly during the first 12 weeks of treatment for close monitoring. People taking Limbitrol DS (chlordiazepoxide and amitriptyline) and those around them should be especially watchful for changes in mood or mental state and report them to a doctor. Limbitrol DS should not be used if you are allergic to the medications amitriptyline, chlordiazepoxide, alprazolam, clorazepate, diazepam, lorazepam or oxazepam. Do not take Limbitrol DS if you are recovering from a heart attack. You should not use Limbitrol DS if you have used a monoamine oxidase inhibitor (MAOI), including isocarboxazid, phenelzine, rasagiline, selegiline, furazolidone or tranylcypromine, within the previous two weeks. Pregnant and breastfeeding women should not use Limbitrol DS, as the medication can cause harm to a fetus and passes through breast milk to a nursing infant. People with certain medical conditions should discuss them with their doctor before taking Limbitrol DS. These conditions include:

  • heart, kidney or liver disease
  • epilepsy
  • seizures
  • mental illness, such as schizophrenia or bipolar disorder
  • alcohol or drug addiction
  • glaucoma
  • thyroid disorders
  • difficulty urinating

People taking Limbitrol DS particularly older adults, may experience drowsiness. Do not drive or engage in activities that require you to be alert until you know how you react to the medication. You should not drink alcohol while using Limbitrol DS. Alcohol can make certain side effects of the medication, such as drowsiness, much worse. Over-the-counter medications that cause drowsiness, such as muscle relaxants, cold medicines and sleeping aids, should also be avoided while using Limbitrol DS.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.