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What should I know about bupivacaine and epinephrine?

Before receiving a bupivacaine-epinephrine injection, you should know that local anesthetics (numbing agents) such as this can cause temporary swelling or puffiness in the injection area. You should know that this anesthetic's affects might last as long as seven hours. During this time it is important not to chew solid foods or test the numb area by probing, as you may injure yourself.

Rare reactions can occur after this injection, including confusion, convulsions, slowed or stopped breathing and cardiovascular problems. You also should know that this solution contains epinepherine, a vasoconstrictor, which contracts blood vessels and helps reduce the amount of bupivacaine that gets absorbed into the blood. If you have high blood pressure (hypertension), heart disease or diabetes, be sure to speak with your doctor before receiving a bupivacaine-epinephrine injection.

Finally, you should know that this injection is not intended for anyone who is sensitive or allergic to it, or to any similar local anesthetic. In addition, bupivacaine-epinephrine injection may interact with certain other drugs to cause severe, long-term hypertension.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.