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Does chloroprocaine interact with other drugs or food?

When chloroprocaine is combined with epinephrine or norepinephrine and is given to people who are on monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, or phenothiazines, prolonged hypotension (low blood pressure) or prolonged hypertension (high blood pressure) may occur. Cerebrovascular accidents and prolonged hypertension can occur from the combined use of vasopressor (for hypotension caused by obstetric nerve blocks) or ergot-type oxytocic medications (to hasten delivery) and chloroprocaine. Sulfonamides should never be used in combination with chloroprocaine.

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