Our Mission

The Pharmaceutical Research and Manufacturers of America (PhRMA) represents the country’s leading pharmaceutical research and biotechnology companies, which are devoted to inventing medicines that allow patients to live longer, healthier, and more productive lives. PhRMA companies are leading the way in the search for new cures. PhRMA members alone invested an estimated $45.8 billion in 2009 in discovering and developing new medicines. Industry-wide research and investment reached a record $65.3 billion in 2009.

Activity

  • PhRMA
    PhRMA answered:
    If your provider recommends that you start taking a new prescription drug, here are some questions to ask:
    •How will the medicine help treat my illness?
    •What are the benefits versus the risks of taking it?
    •What steps can I take to make sure it works best for me?
    •When should I follow up to...Read More
  • PhRMA
    PhRMA answered:
    Patients should follow the directions of their physician and always take their medicines as prescribed. For expired medicines or medicines that are no longer needed, the following guideline for disposal is provided.

    1.Unless product directions say otherwise, do not dispose of unused medicines...Read More
  • PhRMA
    PhRMA answered:
    Scientists' knowledge of disease is growing rapidly and today they are tackling diseases more complex than ever before. Armed with some understanding of how the disease works, the first step in making a new medicine is to identify a specific target that is a promising focal point for a medicine -...Read More
  • PhRMA
    PhRMA answered:
    Once a drug candidate has been identified in the laboratory, it begins years of testing. It starts with lab and animal studies to evaluate its safety and demonstrate that it has biological activity against the disease target. 
    Key preclinical tests include pharmacokinetics, the study of how drugs...Read More
  • PhRMA
    PhRMA answered:
    After preclinical testing is completed, a company files an IND with the U.S. Food and Drug Administration (FDA) prior to beginning any human testing.
    The application must show results of preclinical experiments; the chemical structure of the compound; how it is thought to work in the body; any side...Read More
  • PhRMA
    PhRMA answered:
    Patients can be confident that the drug they are taking has been thoroughly studied and evaluated in a series of clinical trials before the FDA approved it for the public. Nevertheless, there are some important steps patients should take to make sure their medicines are safe for them:
    1) understand...Read More
  • PhRMA
    PhRMA answered:
    The FDA serves as a consumer watchdog—it makes sure that safe and effective drugs are available to improve the health of patients who need them. The FDA evaluates new drugs before they can be sold and ensures that prescription and over-the-counter drugs, both brand name and generic, work correctly and...Read More
  • PhRMA
    PhRMA answered:
    The pharmaceutical industry has two major roles in managing the safety of medicines:
    1) To collect, investigate and proactively evaluate information relating to side effects of medicines during the clinical trials phase.
    2) To vigorously monitor health outcomes and report to the FDA any and all evidence of...Read More
  • PhRMA
    PhRMA answered:
    No drug is 100% safe and effective for all patients. Every drug, whether it is over-the-counter or prescription, carries some risks or potential side effects, and sometimes these side effects don’t become known until after the medicine has been made available to the general patient population. Th...Read More
  • PhRMA
    PhRMA answered:
    Pharmaceutical companies, the FDA, health care providers and patients all play important roles in monitoring drug safety. Once a new medicine is approved, the manufacturer is required to file safety reports with FDA every three months for three years, and then annually for as long as the drug is...Read More
  • PhRMA
    PhRMA answered:
    Drug safety is established incrementally through all stages of the development process. It is assessed early in the process through a series of laboratory tests, animal tests, and then with very small numbers of volunteer patients. Only after it’s clear that a drug is safe for people will it be tested in larger...Read More
  • PhRMA
    PhRMA answered:
    There are more than 3.6 billion prescriptions written per year in the U.S. and for the overwhelming majority of patients, those medicines have proven to be safe and effective.  According to the Food and Drug Administration (FDA), about 97% of the drugs it has approved over the past two decades are still on...Read More
  • PhRMA
    PhRMA answered:
    Although there is always room for improvement in patient safety, the United States has the world's best drug safety record.
    The FDA conducts rigorous reviews of each drug during an approval process that spans 10 to 15 years. FDA regulators thoroughly examine tens of thousands of pages of scientific...Read More
  • PhRMA
    PhRMA answered:
    The safety monitoring continues for medicines long after FDA approval has been granted. Manufacturers are required to notify FDA immediately of any potential issues or concerns about a particular medicine. They also must submit summary reports to the FDA every three months on any "adverse events"...Read More
  • PhRMA
    PhRMA answered:
    In 1992, Congress passed a law to increase the FDA’s resources and expedite the drug review process. The Prescription Drug User Fee Act (PDUFA) imposes fees on pharmaceutical companies for every new drug application they submit. Since PDUFA was enacted, FDA has assessed pharmaceutical companies nearly...Read More