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Healthy habits during a watch-and-wait phase of CLL treatment

Learn how to prioritize your health when you are living with chronic lymphocytic leukemia.

A man chops vegetables. A healthful diet is an important focus when living with leukemia.

Updated on July 16, 2025

Chronic lymphocytic leukemia (CLL) is different from some other cancers in that some people who are diagnosed don’t receive treatment right away. This is because they either don’t need it yet or early treatment could potentially result in complications.

As a result, many people with the slower-growing form of CLL stay in a “watch-and-wait” or “active surveillance” phase for several years. This may be the phase you’re in right now. During this time, you’ll see your doctor regularly for blood tests and will also be asked about any new symptoms you might be experiencing. In addition to continuing with these important checkups, adopting (or maintaining) healthy lifestyle habits is key. Here are some tips and suggestions.

Focus on a healthy, well-rounded diet

When putting your meals together or ordering at a restaurant, try to make vitamin- and nutrient-rich vegetables the centerpiece of your plate. In addition, opt for fish, poultry, and plant-based proteins over red meat. Do your best to avoid processed meats such as cold cuts and hot dogs completely, as these foods can increase your risk for other types of cancer.

When it comes to getting enough fiber, it’s a wise idea to eat plenty of whole grains, lentils, nuts, and seeds. Foods high in omega-3 and monounsaturated fats are a healthy choice, too. Good sources include olive and canola oil, olives, walnuts, chia seeds, flaxseed, avocado, and fatty fish like salmon and Atlantic mackerel.

Keep moving

Exercising regularly is one of the most important things you can do for your health. The list of benefits goes on and on. A regular fitness regimen can help you strengthen your muscles and bones, manage your weight, increase your flexibility, and so much more. It can also be key in boosting your mood and reducing stress. That’s because exercise releases feel-good brain chemicals called endorphins that help enhance your sense of well-being. Working out can be a great social activity, too. Consider setting up a recurring walking date with a friend or family member. You’ll get to catch up with a loved one while doing something beneficial for your body. Before beginning any sort of exercise program, be sure to get the okay from your healthcare team.

Get the sleep you need

Just like exercise, getting adequate sleep has a host of potential physical and mental health benefits, including reduced stress and the ability to think more clearly. It may even lower the risk of infections by helping to support a healthy immune system. Most healthy adults require seven to nine hours of sleep each night.

To help ensure you’re getting enough sleep, consider setting a bedtime and sticking to it—both during the week and on the weekends. This will help your body’s internal clock get used to a regular pattern of when you should be sleeping and when you should be awake. Another tip for ensuring good, quality rest is avoiding screentime before bed. Instead of looking at a television, smartphone, or backlit tablet, consider paging through a magazine or doing some peaceful meditation.

If you smoke, quit

Smoking can negatively affect your health in a number of ways. Smokers are more likely than nonsmokers to develop heart disease, stroke, and a variety of cancers. If you smoke (even occasionally), one of the single best things you can do for your overall health is to kick the habit. Tell your healthcare provider that you want to quit and ask what resources are available to help. There are a variety of online resources available to assist you in becoming smoke-free. A close friend or family member can also be a valuable source of support and can help you stay accountable.

Prioritizing your health

The “watch-and-wait” phase of CLL may feel strange and uncertain at times, and you may be wondering if you’re doing enough. By making smart lifestyle choices and being regularly monitored by your healthcare team, you can feel confident that you’re making your health a priority.  

Article sources open article sources

Leukemia & Lymphoma Society. Watch and Wait. Accessed July 16, 2025.
American Cancer Society. Typical Treatment of Chronic Lymphocytic Leukemia. March 20, 2025.
Danielle Underferth. Processed meat and cancer: What you need to know. MD Anderson Cancer Center. February 2016.
Cleveland Clinic. Why Omega-3s Are Good for You. December 22, 2020.
Mayo Clinic. Omega-3 in fish: How eating fish helps your heart. August 25, 2023.
Centers for Disease Control and Prevention. Physical Activity Basics: Benefits of Physical Activity. April 24, 2024.
Anxiety and Depression Association of American. Physical Activity Reduces Stress. Accessed July 16, 2025.
U.S. Department of Health and Human Services/OASH. Get Enough Sleep. August 6, 2024.
Centers for Disease Control and Prevention. Sleep: About Sleep. May 15, 2024.
Sleep.org. How to Reset Your Sleep Schedule. January 18, 2024.
Smokefree.gov. Reasons to Quit. Accessed July 16, 2025.
Centers for Disease Control and Prevention. Smoking and Tobacco Use: Cigarette Smoking. September 17, 2024.
Smokefree.gov. I Want to Quit. Accessed July 16, 2025.

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