Vitamin E

What is the effect of vitamin E on arthritis?

A Answers (1)

  • AGrant Cooper, MD, Physical Medicine & Rehabilitation, answered
    Vitamin E is a powerful antioxidant. French scientists showed that 6 weeks of vitamin E supplementation in mice reduced the progression of bone and cartilage destruction, when compared with mice that were not given supplements.

    German physicians showed that supplementation with 400 IU of vitamin E daily for 6 weeks reduced pain twice as much as a placebo. Another study found that 400 IU per day of vitamin E relieved arthritis pain symptoms more effectively than nonsteroidal anti-inflammatory drugs (NSAIDs), including aspirin, ibuprofen, and acetaminophen.

    One part of the Framingham study showed that people who consumed 6-11 mg of vitamin E daily were significantly less likely to experience progression of arthritis of the knee than were people who consumed 2-5 mg. These dosages are much lower than usually given; vitamin E toxicity has been seen at doses of 3,000 IU per day for more than 7 weeks.
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What are the health benefits of vitamin E?