At the Brady Urological Institute at Johns Hopkins Medicine, we recommend the following guidelines for prostate cancer screening for men in their 50s:
- If the PSA is below 2.0ng/ml and stable, re-screening should take place at two-year intervals
- If the PSA is above 2.0ng/ml, re-screening should take place annually
- Cancer should be suspected if the PSA velocity is
- Greater than 0.35ng/ml per year when the PSA is below 4.0
- Greater than 0.75ng/ml per year is the PSA is above 4.
- A biopsy should be performed if the PSA is above 3-4ng/ml, depending on personal risk, velocity, and/or an abnormal DRE (digital rectal exam)