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Mark Morocco, Emergency Medicine, answeredSchizoid personality disorder is probably caused by several different factors, including genetic and environmental issues. If your parent or another close relative has schizophrenia or a similar mental illness, you may be at a greater risk of developing schizoid personality disorder. There are several possible environmental causes of schizoid personality disorder too, according to the Mayo Clinic. Young children growing up in unsupportive atmospheres may be more likely to develop a condition like schizoid personality disorder. When parents continuously ignore the emotional needs of a sensitive child, they may cause long-term damage to the child's social and emotional development, leading to the development of schizoid personality disorder later in life.