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Louis Rosner, Neurology, answeredDegenerative is a category of disease in which degeneration occurs in a part of the body due to an unknown cause. An example of a degenerative disease is Alzheimer's, in which brain cells begin to die off for no apparent reason. Although degenerative is a scientifically accepted category, it is basically a wastebasket category for the incurable diseases that have no known cause. Multiple sclerosis (MS) was once in this category, but an overwhelming amount of evidence now points to the probability that MS is caused by infection or allergy.