If you are exposed to harmful toxins or chemicals, it can affect the way the genes in your body work and can potentially cause mutations in your genes that could lead to future disease. However, for his to occur, you generally need a long term exposure to the harmful substance and this varies depending on the environmental toxin/chemical.
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Pina LoGiudice, Naturopathic Medicine, answeredThere are many interactions between genes and environment. About 30% of genes are household genes - and these cannot really change much. In other words, one can personally work on stress and change foods as much as possible, but will still likely keep the same eye color one already has. However, about 70% of genes are changeable to various extents, depending on what we eat, our stressors, our external toxins, nutrient intake, etc… These lifestyle choices will turn up or down the volume of a gene not unlike how you can turn the volume control on a radio speaker.