Dr. Mark O'Rourke

  • Hematology & Oncology
  • , Internal Medicine
  • Greenville, SC
  • Languages supported at his practice: French, English, Spanish
  • Accepting New Patients
  • Electronic Health Records

Dr. O'Rourke's Background


Dr. O’Rourke is a medical oncology cancer specialist with Cancer Centers of the Carolinas and the Medical Director for the GHS Center for Integrative Oncology and Survivorship. He grew up in Santa Barbara, California. He went to Stanford University for undergraduate and served in the U.S. Navy as an instructor at the Naval Nuclear Power School. He went to UCLA for medical school and to the Duke University Medical Center for residency training and fellowships in medical oncology and geriatrics. He has been a member of the medical staff at GHS since 1990. His practice includes blood and cancer illnesses that affect adults. He also participates in the GHS Gastrointestinal Cancer Multidisciplinary Clinic, which specializes in cancers of the stomach, pancreas, bile ducts, liver, and colon. The Center for Integrative Oncology and Survivorship is a separate clinic, which helps cancer survivors regain their full physical, mental, emotional, and spiritual health after cancer treatment. Integrative Oncology addresses the full range of a person’s experience with cancer, including exercise, nutrition, mind-body therapies, social support, and mental and spiritual health. Dr. O’Rourke has had a particular interest in medical ethics and serves on the ethics committees of the South Carolina Medical Association and the American Society of Clinical Oncology. He has taken additional training and become board certified in palliative care, which is a new specialty that addresses symptom control, pain relief, communication, and coordination of care for seriously ill persons. He also sees patients in the GHS Oncology Palliative Care clinic that provides this kind of care for oncology patients. Dr. O’Rourke and his wife, Rita, have two children and two grandchildren. In his free time, he helps Rita in the garden and in the kitchen.

Hospital Affiliations
  • Residency
  • Duke University Medical Center
  • Medical School, 1982
  • University of California Davis School of Medicine
  • Sacramento, CA
Affiliations & Group Memberships